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BioFab 3d Tissues & Organ Printer

Biotechnology
BIOFA
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...believe in replacing organs as a
viable way for life expansion.


 



We firmly believe in replacing organs as a viable way for life expansion.

Either genetics or age our organs deteriorate and end up failing our body.
Given that we work as a whole when one of our parts fail its malfunction involve
other organs and forces them to compensate this shortness . I.e. When the liver stops
working our kidneys pick up the slack and double or triple their functions.
This excessive work will eventually lead to the organs failure and subsequent death.

 





Once identified we start building the needed organ. To achieve the right size and weight
of the organ we use the person muscle mass index calculated with its own height and weight. I.e.
If we wish to replace an esophagus in a person who weighs 70kg and measures 1.70 mt.
(Giving us a muscle mass index of 25) we would have to built a 40 cms esophagus.
We can also use a MRI to get a 3D image and get the measurements we need.


Once identified the organs dimension we start developing it by:



First, creating virtual frame for the organ in a CAD computer program, in order to do so we use the number phi as a base to recreate blood cell paths that will feed the new organs cells. We find Phi and its golden ratio all over the universe: in some mollusk, in tree structures, in sunflowers and our DNA.Biofab has created a computer program based on it and if you wish to learn more about it just let us know.

With the CAD model we fill up our first bioprinters hedpin with the Biofabhidrogel (patented) and begin to create the organ's structure. To know more about our gel please ask us confidentiality. Meanwhile, we obtain -by using our extraction protocol- mesenchymal stem cells from fat or the third molar. 

The extracted stem cells are differentiated and cultivated depending on the organ we will print. i.e. In order to print a esophagus we need endoderm cells, if we wish to print cartilage we will need chondrocytes cells.

 


Once we have the design and biological material, we begin the printing process.

Printing is done layer upon layer. First a layer of Hydrogel is printed as a frame, then the differentiated stem cells. By printing first the frame we can inject up to 17 nanomilimeters of biological material in the different paths we first made: G1 path (straight), G2 (semicircle), G3 (tangent) and G4 (cotangent).

Since printing is done from the inside out, it can leave cavities of a thickness 10 times lower than the human hair, it is through this cavities that runs blood to feed the organ bringing it to life. That is the reason the process of printing one organ can be segmented and take quite a long time, about 10 hours to print a right knee cartilage and up to 48 hours to print an esophagus.

Once the organ is printed and loaded with biological material from stem cells it is brought to a bioreactor where it will be fed and cultivated to help its cells replicate in dozens of millions. When the feeding and vascularity processes finish then the organ is transplanted to the human body.







 


Currently we have the following services and products that have generated an interesting cash flow 


1. Cryopreservation of umbilical cord stem cells, adipose tissue and the third molar – Since April, 2015

2. Differentiation and multiplication of stem cells – Since August, 2015

3. Classes for extraction, differentiation, cryopreservation and stem cell application – Since October, 2015

4. BioPrinter Biofab sales - Since November, 2015

5. Cartilage and non compact organs printing - since December , 2015


At the moment we are building a couple of printers for our costumers
in Canada and China thereby expanding our services to materials sale
and 3D printing training. We are also preparing our first 3D digital printing
course, using our own bioprinter. At the end of 2016 we wil be touring
medical and technological fairs to introduce our product to the world.

 





My name is Cesar Loo and I am a serial entrepreneur. In my 40 years I have managed to built 5 successful bussines, have 2 millionaire exits and survive 2 failures. Right now I am focused on giving Biofab a billion dollar appraisal over a 2 and half year period, and i am on the right track: so far, after only a year and half, I have won start up chile, start up Perú, start up health and 500 start up. Currently Bio Fab Inc has a 7.2 mmd valuation, 2 patents, a positive sales flow and over 500 costumers.

We have launched this crowdfunding campaign searching for your support, 
because we have 2 BioPrinter orders from universities in Vancouver and Ho chi min. Each BioPrinter goes at a 400k price and making them cost 200k approx so our profit margin is quite good but even better is that we will also be working together I+D+i, with technological transference and selling materials, establishing long term relationships with them. With your money we can make it happen. We take Visa or we can give you a bank account number.


The line for a new organ transplantation is getting longer every day. The problem can be seen not only in lack of actual donors at the particular moment, but also in the waiting time. To give an example, the median waiting time for an individual’s first kidney transplant is 3.6 years and can vary depending on health, compatibility and availability of organs. 

 In 2003, Cesar’s grandmother died from a liver cancer. Full of hope and optimism, the family was waiting to hear the happy news from the doctors that there is a donor. Unfortunately, this day never came. Life showed its dark side and Cesar’s grandmother passed away. 

 “Eleven years later I still remember her pain,” says Cesar. This unfortunate event in Cesar’s life was the main reason why he asked himself: why not create a technology for printing human organs? This is how BioFab came into being.

Be part of BioFab's Solution!




I thought of becoming a person who wanted to extend people's lifes. The process starts with our Bank of organs, where the extracted  stem cells are saved. The stem cells can be extracted from the umbilical cord, third molar or body fat. Then comes the "Print Phase". The needed organ is designed so the Bio printer can build the scaffold's organ at the same time the stem cells are injected. Those injected stem cells were converted to simulate the job of the needed organ.

What is Stem Cell?

Stem cells are the building blocks of life and the body’s primary repair mechanism.
They are defined by being able to differentiate into any of the 9 types of tissue in
the body, such as heart, bone, cartilage, lung or kidney, when injury occurs.
A stem cell can also replicate without limit throughout one’s life.
This is Biological Material for BioPrinter

How much does it cost?

Prices vary based on the disease or condition,
but we estimate that each patient will pay on from
USD10,000 until USD 150,000 per Organs or Tissue.

How much does it cost of BioPrinter?

The BioPrinter cost around of USD400,00.00 for corporation.
Special price for University USD150,000.00 more I+D+i, transfer protocol
and 10% of revenue on products and service developep with BioPrinter and University






Hospitals, Clinics, Universities for research, Final users.

Why Should I invest in this OPPORTUNITY?

Here's a chance to create a lasting legacy by helping millions of people suffering from various degenerative diseases and at the same time earn an attractive return on your investment. Investors participate in the profits of the three facilities that will be built by BioFab Inc. We project that passive income distributions will average 25% over the first five years. The 5 yr ROI could be as high as 10X with capital gains.

 

Currently we have the following services and products that have generated an interesting cash flow 
 

1. Cryopreservation of umbilical cord stem cells, adipose tissue and the third molar – Since April, 2015

2. Differentiation and multiplication of stem cells – Since August, 2015

3. Classes for extraction, differentiation, cryopreservation and stem cell application – Since October, 2015

4. BioPrinter Biofab sales - Since November, 2015

5. Cartilage and non compact organs printing - since December , 2015

At the moment we are building a couple of printers for our costumers in Canada and China thereby expanding our services to materials sale and 3D printing training. We are also preparing our first 3D digital printing course, using our own bioprinter. At the end of 2016 we wil be touring medical and technological fairs to introduce our product to the world.

 We invite you to be part of BioFab's solution!





Where will we be in 2 years? 

In 2 years BioFab will increase its printing services to compact bodies, such as liver, kidney, pancreas.
Also we will be selling biological printers at a lower cost than the current (USD400,000.00)
and expanding our printing services to hospitals and universities on demand.

Also, today we are preparing to launch BioFab as an IPO in late 2018 at
a minimum valuation of 2,000,000,000.00

BioFab's path and the next steps to more success



Cesar Loo - Founder - 
Entrepreneur , Scientist, Serial Entrepreneur . In my 21 years as an entrepreneur I have 5 companies successfully working, 
2 exit and 2 Failures

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  • 22/10/16 11:38

    BioFab — Startup of The Week

    #BIFINCS16 Incubator Program Spring 2016 | Netherlands

    Have you ever wondered what the companies like Mars, Walmart, Volkswagen and Samsung Electronics have in common? They are all family-owned enterprises, and so is BioFab. Founded in 2014 by Cesar Loo Gil and his father-in-law Ricardo Garcia, BioFab uses a 3D bioprinter to produce various parts of a human body. This week we are happy to tell you their story.

    https://medium.com/our-program-updates/biofab-startup-of-the-week-4c6d4f55fdeb#.vjkwy7xzw
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